Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/49075
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Oliveira, Cláudio Duarte | por |
dc.contributor.author | Rodrigues, Fernando José dos Santos | por |
dc.contributor.author | Gonçalves, Samuel M. | por |
dc.contributor.author | Goldman, Gustavo H. | por |
dc.contributor.author | Carvalho, Agostinho Albérico Rodrigues | por |
dc.contributor.author | Cunha, Cristina Amorim | por |
dc.date.accessioned | 2018-01-08T12:22:48Z | - |
dc.date.available | 2018-01-08T12:22:48Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 2235-2988 | - |
dc.identifier.uri | https://hdl.handle.net/1822/49075 | - |
dc.description.abstract | Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are an increasing cause of fungal disease among immunocompromised hosts, such as hematological patients and solid organ transplant recipients. The initiation of commensal or pathogenic programs by Trichosporon spp. involves the adaptation to the host microenvironment and its immune system. However, the exact virulence factors activated upon the transition to a pathogenic lifestyle, including the intricate biology of the cell wall, and how these interact with and subvert the host immune responses remain largely unknown. Here, we revisit our current understanding of the virulence attributes of Trichosporon spp., particularly T. asahii, and their interaction with the host immune system, and accommodate this knowledge within novel perspectives on fungal diagnostics and therapeutics. | por |
dc.description.sponsorship | This work was supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER) (NORTE-01-0145-FEDER000013), and by Fundação para a Ciência e Tecnologia (FCT) (IF/00735/2014 to AC, and SFRH/BPD/96176/2013 to CC). | por |
dc.language.iso | eng | por |
dc.publisher | Frontiers Media | por |
dc.relation | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F96176%2F2013/PT | por |
dc.rights | openAccess | por |
dc.subject | Trichosporon | por |
dc.subject | Trichosporonosis | por |
dc.subject | Virulence factors | por |
dc.subject | Host-pathogen interaction | por |
dc.subject | Antifungal immunity | por |
dc.title | The cell biology of the Trichosporon-Host interaction | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.frontiersin.org/journals/cellular-and-infection-microbiology# | por |
oaire.citationStartPage | 118 | por |
oaire.citationEndPage | 118 | por |
oaire.citationIssue | 118 | por |
oaire.citationVolume | 7 | por |
dc.date.updated | 2017-12-19T16:04:50Z | - |
dc.identifier.doi | 10.3389/fcimb.2017.00118 | por |
dc.identifier.pmid | 28439501 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Frontiers in Cellular and Infection Microbiology | por |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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2017.duarte-oliveira c.the cell biology of the trichosporon-host interaction.pdf | 917,84 kB | Adobe PDF | Ver/Abrir |