Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/50582
Título: | Biomechanical considerations in the pathogenesis of osteoarthritis of the knee |
Autor(es): | Heijink, Andras Gomoll, Andreas H. Madry, Henning Drobnič, Matej Filardo, Giuseppe Espregueira-Mendes, João Van Dijk, C. Niek |
Palavras-chave: | Aging Animals Anterior Cruciate Ligament Injuries Biomechanical Phenomena Cartilage, Articular Chondrocytes Comorbidity Homeostasis Humans Joint Instability Knee Joint Osteoarthritis, Knee Oxidative Stress Rupture Malalignment Meniscus Osteochondral defects Joint instability Pathology Etiology Cartilage |
Data: | Mar-2012 |
Editora: | Springer |
Revista: | Knee Surgery, Sports Traumatology, Arthroscopy |
Resumo(s): | Osteoarthritis is the most common joint disease and a major cause of disability. The knee is the large joint most affected. While chronological age is the single most important risk factor of osteoarthritis, the pathogenesis of knee osteoarthritis in the young patient is predominantly related to an unfavorable biomechanical environment at the joint. This results in mechanical demand that exceeds the ability of a joint to repair and maintain itself, predisposing the articular cartilage to premature degeneration. This review examines the available basic science, preclinical and clinical evidence regarding several such unfavorable biomechanical conditions about the knee: malalignment, loss of meniscal tissue, cartilage defects and joint instability or laxity. Level of evidence IV. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/50582 |
DOI: | 10.1007/s00167-011-1818-0 |
ISSN: | 0942-2056 |
e-ISSN: | 1433-7347 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Biomechanical considerations in the pathogenesis of osteoarthritis of the knee (2011).pdf Acesso restrito! | 291,37 kB | Adobe PDF | Ver/Abrir |