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https://hdl.handle.net/1822/51975| Título: | The reaction of 2-(Acylamino) benzonitriles with primary aromatic amines: A convenient synthesis of 2-substituted 4-(Arylamino) quinazolines |
| Autor(es): | Marinho, Elina Margarida Ribeiro Proença, M. Fernanda R. P. |
| Palavras-chave: | acylation cyclization heterocycles 4-aminoquinazolines 2-aminobenzonitrile |
| Data: | 2015 |
| Editora: | Georg Thieme Verlag |
| Revista: | Synthesis |
| Resumo(s): | 2-Substituted 4-(arylamino) quinazolines were prepared from 2-(acylamino) benzonitriles and primary arylamines by refluxing in either ethanol using trifluoroacetic acid as a catalyst or acetic acid. The 2-aminobenzonitrile was acylated by reaction with anhydrides, isocyanates, or ethyl chloroformate at room temperature. |
| Tipo: | Artigo |
| URI: | https://hdl.handle.net/1822/51975 |
| DOI: | 10.1055/s-0034-1380322 |
| ISSN: | 0039-7881 |
| Arbitragem científica: | yes |
| Acesso: | Acesso restrito UMinho |
| Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| rp-ss-2015-z0006-op.pdf Acesso restrito! | 884,86 kB | Adobe PDF | Ver/Abrir |
