Benzoxazole derivatives as phototriggers for the release of butyric acid

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Campo DC	Valor	Idioma
dc.contributor.author	Soares, Ana Maria Silva	por
dc.contributor.author	Costa, Susana P. G.	por
dc.contributor.author	Gonçalves, M. Sameiro T.	por
dc.date.accessioned	2018-03-29T15:29:26Z	-
dc.date.available	2018-03-29T15:29:26Z	-
dc.date.issued	2015	-
dc.identifier.citation	A. M. S. Soares, S. P. G. Costa, M. S. T. Gonçalves, Benzoxazole derivatives as phototriggers for the release of butyric acid. In Proceedings of the 18th Int. Electron. Conf. Synth. Org. Chem., Sciforum Electronic Conference Series, Vol. 18, 2015, a034.	por
dc.identifier.isbn	978-3-906980-55-3	por
dc.identifier.uri	https://hdl.handle.net/1822/53761	-
dc.description.abstract	With the aim of evaluating the application of new benzoxazole derivatives as photoactive moiety in butyric acid prodrugs, ester conjugates were synthesized by reaction of the chloromethylated heterocyclic precursors with the model drug. Photocleavage studies of the conjugates in methanol/HEPES buffer (80:20) solutions at different wavelengths of irradiation (254, 300 and 350 nm) confirmed the quantitative release of the butyric acid in short irradiation times.	por
dc.language.iso	eng	por
dc.publisher	MDPI	por
dc.relation	info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F80813%2F2011/PT	por
dc.relation	info:eu-repo/grantAgreement/FCT/COMPETE/132953/PT	por
dc.rights	openAccess	por
dc.subject	benzoxazole	por
dc.subject	photorelease	por
dc.subject	photocleavable protecting groups	por
dc.subject	prodrugs	por
dc.subject	butyric acid	por
dc.title	Benzoxazole derivatives as phototriggers for the release of butyric acid	por
dc.type	conferencePaper	por
dc.peerreviewed	yes	por
dc.comments	Artigo publicado nas atas de conferência resultante da comunicação a034.	-
oaire.citationConferenceDate	1 - 30 November 2014	por
sdum.event.title	18th International Electronic Conference on Synthetic Organic Chemistry	por
sdum.event.type	conference	por
dc.subject.fos	Ciências Naturais::Ciências Químicas	por
dc.description.publicationversion	info:eu-repo/semantics/publishedVersion	por
sdum.conferencePublication	Proceedings of the 18th International Electronic Conference on Synthetic Organic Chemistry	por
Aparece nas coleções:	CDQuim - Comunicações e Proceedings

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