Synergetic efect between phage and antibiotics as an alternative strategy to control Pseudomonas aeruginosa biofilm associated infections

Abstract

[Excerpt] Bacterial biofilms are sessile microbial aggregates with unique community properties, showing a high degree of tolerance/resistance to disinfection by chemicals, antibiotics, and to the human immune system. The opportunistic pathogen Pseudomonas aeruginosa is one of the most frequent causes of biofilm-associated infections, causing infections extremely difficult to treat. Currently, bacteriophages (phages) are becoming a potential solution for the treatment of such infections. [...]