Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/67190
Título: | Transient elastography: should XL probe be used in all overweight patients? |
Autor(es): | Arieira, Cátia Monteiro, Sara Xavier, Sofia Castro, Francisca Dias de Magalhães, Joana Fernandes Silva Marinho, Carla Pinto, Rui Costa, Washington Correia, José Pinto Cotter, José Almeida Berkeley |
Palavras-chave: | Adult Body Mass Index Elasticity Imaging Techniques Equipment Design Female Humans Liver Liver Cirrhosis Logistic Models Male Middle Aged Multivariate Analysis Non-alcoholic Fatty Liver Disease Obesity Overweight Prospective Studies Reproducibility of Results Sensitivity and Specificity Transducers Transient elastography Liver steatosis Liver fibrosis |
Data: | Ago-2019 |
Editora: | Taylor & Francis |
Revista: | Scandinavian Journal of Gastroenterology |
Resumo(s): | Background: Obesity is one of the main factors of transient elastography (TE) failure, considering body mass index (BMI) ≥28 kg/m2 as a limiting factor. The XL probe was designed to overcome this limitation. Aim: To compare the feasibility of the M and XL probes in patients with BMI ≥ 28 kg/m2, to evaluate differences in mean values of controlled attenuation parameter (CAP) and liver stiffness measurement (LSM) between the two probes and find predictive factors of TE failure. Material and methods: Prospective study, including all patients with BMI ≥ 28 kg/m2 consecutively admitted for TE. Results: Included 161 patients. Measurements with M probe were reliable in 69.6% of the patients, with 68.2% of valid measurements in obese population and 58.9% in patients with skin-capsule distance (SCD) >25 mm. In 40 patients (81.6%) with an invalid M probe measurement, a reliable result was obtained with XL probe. We found that SCD >25 mm was the only predictor of M probe failure (OR: 4.9, CI: 1.64-14.63, p = .004). In those patients in which TE was possible with both probes (n = 112), mean CAP was 304 ± 49 dB/m2 with M probe and 301 ± 50 dB/m2 with XL probe (p = .59). Regarding liver stiffness, a mean value of 7.58 ± 3.47 kpas was obtained with the M probe and 6.21 ± 3.44 kpas with the XL probe (p < .001). Conclusion: There is a reliable applicability of the M probe in a high number (68.2%) of patients with a BMI ≥30 kg/m2. A SCD >25 mm was the only predictive factor of M probe failure. Mean values of LSM with XL probe were lower than those obtained with M probe. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/67190 |
DOI: | 10.1080/00365521.2019.1644367 |
ISSN: | 0036-5521 |
e-ISSN: | 1502-7708 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito autor |
Aparece nas coleções: | ICVS - Artigos em revistas internacionais / Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
arieira2019.pdf Acesso restrito! | 748,58 kB | Adobe PDF | Ver/Abrir |