Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/69645
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Campo DC | Valor | Idioma |
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dc.contributor.author | Teixeira, Jean Valdir Uchôa | por |
dc.contributor.author | Maia, F. Raquel | por |
dc.contributor.author | Carvalho, Mariana R. | por |
dc.contributor.author | Reis, R. L. | por |
dc.contributor.author | Oliveira, J. M. | por |
dc.contributor.author | Lisboa-Filho, Paulo Noronha | por |
dc.contributor.author | Claro, Ana Paula Rosifni Alves | por |
dc.date.accessioned | 2021-01-25T12:06:34Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.citation | Teixeira J. V. U., Maia F. R., Carvalho M. R., Reis R. L., Oliveira J. M., Lisboa-Filho P. N., Claro A. P. R. A. Synthesis of mussel-inspired poly(dopamine)-gallium nanoparticles for biomedical applications, Nanomedicine, doi:10.2217/nnm-2020-0312, 2021 | por |
dc.identifier.issn | 1743-5889 | por |
dc.identifier.uri | https://hdl.handle.net/1822/69645 | - |
dc.description.abstract | Aim: In this work, we established a simple, controlled, and reproducible method to synthesize gallium-coated polydopamine (PDA) nanoparticles. Methods: Polydopamine was synthetized in the alkali medium with posterior gallium shell formation due to ion chelation on the nanoparticle surface. Results: The obtained results with EDS spectra confirmed the incorporation of gallium on PDA surface. The cytotoxicity of Ga-coated PDA nanoparticles was evaluated in vitro at different concentrations in contact with human adipose-derived stem cells (hASCs). Further cell analysis also demonstrated the benefit of Ga-coated PDA, which increased the cell proliferation rate compared to non-coated PDA. Conclusion: This study indicated that gallium could work as an appropriate shell for PDA particles, inducing cell proliferation at the analyzed concentrations. | por |
dc.description.sponsorship | This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001 and CAPES/UNESP- Print Project. The FRA Maia acknowledges the Portuguese Foundation for Science and Technology (FCT) for her contract under the Transitional Rule DL 57/2016 (CTTI-57/18-I3BS(5)) and JM Oliveira for the financial support provided under the program ‘Investigador FCT’ (IF/01285/2015). M Carvalho thanks the IET Institution of Engineering and Technology for the financial support provided under the IET Harvey Research Prize 2017. | por |
dc.language.iso | eng | por |
dc.publisher | Future Medicine | por |
dc.relation | IF/01285/2015 | por |
dc.relation | CTTI-57/18-I3BS(5) | por |
dc.rights | restrictedAccess | por |
dc.subject | Core/shell | por |
dc.subject | Cytotoxicity | por |
dc.subject | Gallium incorporation | por |
dc.subject | Nanoparticle synthesis | por |
dc.title | Synthesis of mussel-inspired polydopamine-gallium nanoparticles for biomedical applications | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.futuremedicine.com/doi/10.2217/nnm-2020-0312 | por |
dc.comments | http://3bs.uminho.pt/node/20412 | por |
oaire.citationStartPage | 5 | por |
oaire.citationEndPage | 17 | por |
oaire.citationIssue | 1 | por |
oaire.citationVolume | 16 | por |
dc.date.updated | 2021-01-21T14:15:27Z | - |
dc.identifier.eissn | 1748-6963 | por |
dc.identifier.doi | 10.2217/nnm-2020-0312 | por |
dc.date.embargo | 10000-01-01 | - |
dc.identifier.pmid | 33410334 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Nanomedicine | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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20412-Synthesis of mussel-inspired polydopamine-gallium nanoparticles for biomedical applications.pdf Acesso restrito! | 4,25 MB | Adobe PDF | Ver/Abrir |