Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/76633
Título: | Biomaterials and bioactive natural products from marine invertebrates: from basic research to innovative applications |
Autor(es): | Romano, Giovanna Almeida, Mariana Dias Coelho, Ana Varela Cutignano, Adele Gonçalves, Luis G. Hansen, Espen Khnykin, Denis Mass, Tali Ramšak, Andreja Rocha, Miguel Soares Silva, Tiago H. Sugni, Michela Ballarin, Loriano Genevière, Anne-Marie |
Palavras-chave: | Bioactivity Marine biomaterials Marine invertebrates Marine natural products Stem cells |
Data: | Mar-2022 |
Editora: | Multidisciplinary Digital Publishing Institute (MDPI) |
Revista: | Marine Drugs |
Citação: | Romano G., Mariana A., Coelho A. V., Cutignano A., Gonçalves L. G., Hansen E., Khnykin D., Mass T., Ramšak A., Rocha M. S., Silva T. H., Sugni M., Ballarin L., Geneviere A. - M. Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications, Marine Drugs, Vol. 20, Issue 4, pp. 219, doi:10.3390/md20040219, 2022 |
Resumo(s): | Aquatic invertebrates are a major source of biomaterials and bioactive natural products that can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling products and biomaterials. Symbiotic microorganisms are often the real producers of many secondary metabolites initially isolated from marine invertebrates; however, a certain number of them are actually synthesized by the macro-organisms. In this review, we analysed the literature of the years 2010–2019 on natural products (bioactive molecules and biomaterials) from the main phyla of marine invertebrates explored so far, including sponges, cnidarians, molluscs, echinoderms and ascidians, and present relevant examples of natural products of interest to public and private stakeholders. We also describe omics tools that have been more relevant in identifying and understanding mechanisms and processes underlying the biosynthesis of secondary metabolites in marine invertebrates. Since there is increasing attention on finding new solutions for a sustainable large-scale supply of bioactive compounds, we propose that a possible improvement in the biodiscovery pipeline might also come from the study and utilization of aquatic invertebrate stem cells. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/76633 |
DOI: | 10.3390/md20040219 |
ISSN: | 1660-3397 |
Versão da editora: | https://www.mdpi.com/1660-3397/20/4/219 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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20746-marinedrugs-20-00219.pdf | 5,67 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons