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https://hdl.handle.net/1822/79260
Título: | Development of a realistic in vitro digestion model (RGM) coupled UV-VIS-SWNIR fibre optics spectroscopy |
Autor(es): | Madalena, Daniel Alexandre Silva Pinheiro, A. C. Ramos, Oscar Vicente, A. A. |
Data: | 3-Mai-2022 |
Citação: | Madalena, Daniel A.; Pinheiro, Ana Cristina; Ramos, Oscar; Vicente, António A., Development of a realistic in vitro digestion model (RGM) coupled UV-VIS-SWNIR fibre optics spectroscopy. ICFD 2022 - 7th International Conference on Food Digestion. No. 53, Cork, Ireland, May 3-5, 101, 2022. |
Resumo(s): | Background: The development of realistic gastric models unlocked the possibility of studying important digestion phenomena occurring during the digestion of food (e.g., retropulsion). Understanding the dynamics of food digestion in real-time, without sample manipulation, is still a challenge, but brings a huge potential in providing important insights regarding the dynamic process of food digestion (e.g., real time nutrient release kinetics) This study presents a realistic 3D printed in vitro gastric model coupled with ultraviolet-visibleshort- wave-near-infrared (UV-VIS-SWNIR) spectroscope that can be used for real time quantification of nutrients/bioactive compounds. Methods: The INFOGEST semi-dynamic in vitro protocol was used to simulate the digestion of rice (model food). The spectroscope was calibrated for glucose analysis, and the spectra were pre-processed and both chemometric and machine learning techniques were used for glucose quantification using the correlation coefficient as assessment metric. Results: The machine learning algorithms showed to be more accurate at predicting glucose release during the in vitro gastric digestion. Conclusions: The gastric compartment development techniques provide the opportunity to develop a potential standard dynamic in vitro gastric model. Furthermore, it was possible to accurately measure and quantify glucose release during the in vitro digestion process, in real time, using UV-VIS-SWNIR fibre optics spectroscopic. |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/79260 |
Versão da editora: | https://www.icfd2022.com/ |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
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Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_55668_1.pdf | 307,27 kB | Adobe PDF | Ver/Abrir |