Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/82947
Título: | Enhanced photodynamic therapy: a review of combined energy sources |
Autor(es): | Rodrigues, José Artur Oliveira Correia, J. H. |
Palavras-chave: | Photodynamic therapy Non-visible radiation Ultrasound Electric field Magnetic field Synergistic strategies |
Data: | 2022 |
Editora: | MDPI |
Revista: | Cells |
Citação: | Rodrigues, J.A.; Correia, J.H. Enhanced Photodynamic Therapy: A Review of Combined Energy Sources. Cells 2022, 11, 3995. https://doi.org/10.3390/cells11243995 |
Resumo(s): | Photodynamic therapy (PDT) has been used in recent years as a non-invasive treatment for cancer, due to the side effects of traditional treatments such as surgery, radiotherapy, and chemother apy. This therapeutic technique requires a photosensitizer, light energy, and oxygen to produce reactive oxygen species (ROS) which mediate cellular toxicity. PDT is a useful non-invasive therapy for cancer treatment, but it has some limitations that need to be overcome, such as low-light-penetration depths, non-targeting photosensitizers, and tumor hypoxia. This review focuses on the latest innovative strategies based on the synergistic use of other energy sources, such as non-visible radiation of the electromagnetic spectrum (microwaves, infrared, and X-rays), ultrasound, and electric/magnetic fields, to overcome PDT limitations and enhance the therapeutic effect of PDT. The main principles, mechanisms, and crucial elements of PDT are also addressed |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/82947 |
DOI: | 10.3390/cells11243995 |
ISSN: | 2073-4409 |
Versão da editora: | https://www.mdpi.com/2073-4409/11/24/3995 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CMEMS - Artigos em revistas internacionais/Papers in international journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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cells-11-03995.pdf | 2,7 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons