Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/85585
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Sousa, Lúcia | por |
dc.contributor.author | Almeida, Carina | por |
dc.contributor.author | Muzny, Christina A. | por |
dc.contributor.author | Cerca, Nuno | por |
dc.date.accessioned | 2023-07-20T09:43:47Z | - |
dc.date.available | 2023-07-20T09:43:47Z | - |
dc.date.issued | 2023-06-23 | - |
dc.identifier.citation | Sousa, L.G.V., Almeida, C., Muzny, C.A. et al. Development of a Prevotella bivia PNA probe and a multiplex approach to detect three relevant species in bacterial vaginosis-associated biofilms. npj Biofilms Microbiomes 9, 42 (2023). https://doi.org/10.1038/s41522-023-00411-6 | por |
dc.identifier.issn | 2055-5008 | por |
dc.identifier.uri | https://hdl.handle.net/1822/85585 | - |
dc.description.abstract | Bacterial vaginosis (BV) is the most common vaginal infection worldwide. We developed a peptide nucleic acid (PNA) probe targeting Prevotella bivia, a common BV-associated bacteria, and optimized a multiplex approach for detection of Gardnerella spp., P. bivia and Fannyhessea vaginae. Our P. bivia PNA probe specifically detected the target species, and the optimized multiplex approach was able to detect the presence of the three species in multi-species BV biofilms. | por |
dc.description.sponsorship | This work was supported by the National Institute of Allergy and Infectious Diseases [R01AI146065-01A1 to CAM]. It was also partially funded by the Portuguese Foundation for Science and Technology (FCT), under the scope of the strategic funding of unit [UIDB/04469/2020]. L.S. acknowledges FCT the financial support of individual Grant [2020.04912.BD]. | por |
dc.description.sponsorship | A U.S. Provisional Patent Application No. 63/355,887 (UAB Ref No. U22-031/KT Ref No. 035979-1329130-217PV1) has been filed regarding this work entitled “Nucleic Acid Probes and Their Use for the Detection of Prevotella bivia.” | por |
dc.language.iso | eng | por |
dc.publisher | Nature Publishing Group | por |
dc.relation | info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04469%2F2020/PT | por |
dc.relation | info:eu-repo/grantAgreement/FCT/POR_NORTE/2020.04912.BD/PT | por |
dc.rights | openAccess | por |
dc.subject | Biofilms | por |
dc.subject | Infectious-disease diagnostics | por |
dc.title | Development of a Prevotella bivia PNA probe and a multiplex approach to detect three relevant species in bacterial vaginosis-associated biofilms | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | https://www.nature.com/articles/s41522-023-00411-6 | por |
dc.comments | CEB56343 | por |
oaire.citationIssue | 42 | por |
oaire.citationVolume | 9 | por |
dc.date.updated | 2023-07-19T21:24:14Z | - |
dc.identifier.doi | 10.1038/s41522-023-00411-6 | por |
dc.identifier.pmid | 37353508 | por |
dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | - |
sdum.journal | npj Biofilms and Microbiomes | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_56343_1.pdf | 1,17 MB | Adobe PDF | Ver/Abrir |