Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/86996
Título: | Valorisation of the invasive macroalgae Undaria pinnatifida (Harvey) Suringar for the green synthesis of gold and silver nanoparticles with antimicrobial and antioxidant potential |
Autor(es): | González-Ballesteros, Noelia Fernandes, Mário Machado, Raul Sampaio, Paula Gomes, Andreia C. Cavazza, Antonella Bigi, Franca Rodríguez-Argüelles, Maria Carmen |
Palavras-chave: | Undaria pinnatifida Green synthesis Silver nanoparticles Gold nanoparticles Antibacterial activity Antifungal activity |
Data: | 9-Jul-2023 |
Editora: | Multidisciplinary Digital Publishing Institute (MDPI) |
Revista: | Marine Drugs |
Citação: | González-Ballesteros, N.; Fernandes, M.; Machado, R.; Sampaio, P.; Gomes, A.C.; Cavazza, A.; Bigi, F.; Rodríguez-Argüelles, M.C. Valorisation of the Invasive Macroalgae Undaria pinnatifida (Harvey) Suringar for the Green Synthesis of Gold and Silver Nanoparticles with Antimicrobial and Antioxidant Potential. Mar. Drugs 2023, 21, 397. https://doi.org/10.3390/md21070397 |
Resumo(s): | Bacterial and fungal infections are a challenging global problem due to the reported increasing resistance of pathogenic microorganisms to conventional antimicrobials. Nanomaterials are a promising strategy to fight infections caused by multidrug-resistant microbes. In this work, gold (Au@UP) and silver (Ag@UP) nanoparticles were produced for the first time by green synthesis using an aqueous extract of the invasive macroalgae <i>Undaria pinnatifida</i> (UP). The nanoparticles were characterized by a wide range of physicochemical techniques. Au@UP and Ag@UP demonstrated to be spherical and crystalline with an average size of 6.8 ± 1.0 nm and 14.1 ± 2.8 nm, respectively. Carbohydrates and proteins of the UP extract may participate in the synthesis and capping of the nanoparticles. The UP extract, Ag@UP, and Au@UP were assessed for their antimicrobial activity against <i>Escherichia coli</i>, <i>Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans</i>, and <i>Candida auris.</i> Ag@UP showed the highest antimicrobial activity with very low MIC and MBC values for all the tested bacteria, and Au@UP demonstrated to be very effective against biofilm-producing bacteria. The antifungal properties of both Ag@UP and Au@UP were remarkable, inhibiting hyphae formation. This study points towards a very promising biomedical exploitation of this invasive brown algae. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/86996 |
DOI: | 10.3390/md21070397 |
e-ISSN: | 1660-3397 |
Versão da editora: | https://www.mdpi.com/1660-3397/21/7/397 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CBMA - Artigos/Papers |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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marinedrugs-21-00397-v2.pdf | 4,38 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons