Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/89972
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Nascimento, A. | por |
dc.contributor.author | Abreu, C. | por |
dc.contributor.author | Silva, M. | por |
dc.contributor.author | Leite, B. | por |
dc.contributor.author | Rouly, S. | por |
dc.contributor.author | Abreu, Maria José | por |
dc.contributor.author | Ferraz, R. | por |
dc.contributor.author | Costa, M. | por |
dc.contributor.author | Prudêncio, | por |
dc.contributor.author | Parente, E. | por |
dc.contributor.author | Vieira, M. | por |
dc.date.accessioned | 2024-03-25T14:45:37Z | - |
dc.date.available | 2024-03-25T14:45:37Z | - |
dc.date.issued | 2022-12-01 | - |
dc.date.submitted | 2022-05-09 | - |
dc.identifier.citation | Vieira, M., Nascimento, A. M., Abreu, C., Leite, B. ., Silva, M., Abreu, M. J., Ferraz, R. ., Rouly, S. ., Parente, E. ., Costa, M. ., & Prudêncio, C. (2022). Development of a new technology to detect respiratory infectious diseases. InSTEMM Journal, 1(S2). https://doi.org/10.56725/instemm.v1iS2.13 | por |
dc.identifier.issn | 2753-6939 | por |
dc.identifier.uri | https://hdl.handle.net/1822/89972 | - |
dc.description.abstract | The Covid-19 pandemic brought the need to use social masks to prevent the spread of the SARS-CoV-2 virus. However, no reliable and fast method were yet established to detect viral particles and to improve the protective ability of social masks. Through color changes, colorimetric biosensors can be used as a rapid and easily approach to detect virus. Gold nanoparticles (AuNP) are known to have excellent optical properties and huge research potential. The new SARS-CoV-2 has the ability of entering human body cells, namely through a second pathway of entry – the sialic acid (SA) receptor. In order to respond to the emergency and to contribute to the diminishing of the spread of SAR-CoV-2, we developed a colorimetric biosensor based on the functionalization AuNP by sialic acid (SA) (SA-AuNP), as a new and effective textile coating layer, to provide a direct indication of the protective capacity of social masks. To do that, AuNPs (10 nm) were functionalized with SA (SA-AuNP), in three different concentrations (50-50, 30-70 and 20-80, respectively) to select the optimal concentration for respiratory virus detection. Fourier-transform infrared spectroscopy (FTIR) and Scanning Electron Microscope with a Transmission Detector (STEM) analyses confirmed SA-AuNPs binding. FTIR results showed a well-established bond, through matches of peaks of SA-AuNPs. Bindings between the compounds were more evident in 50-50 concentration of SA-AuNP. In the 30-70 SA-AuNP the STEM images show some superposition of the nanoparticles and not so evident binding, as in the 20-80 concentration. Still, between these last two concentrations, the 30-70 is the one that shows the best results since it is visible some circular points larger than the others. To achieve the goal, the concentrations 30-70 and 50-50 of SA-AuNP were impregnated (Textile Foulard) in two substrates of different compositions, a cellulosic and a synthetic one. However, in this technique there are many parameters, such as drying time and temperature, which were varied to understand which the best procedure was to obtain the biosensor. | por |
dc.description.sponsorship | This project was funded under the COVID-19 pandemic andpromoted by the Polytechnic Institute of Porto, together withClothius, Tecelagem, Lda, and co-financed by COMPETE2020 under the R&D Enterprise and Infrastructure Testingand Optimization Incentive System (COVID-19), involved anamount of 169 thousand euros, resulting in a FEDER incentiveof about 135 thousand euros. We thank everyone involved inthis project to make it possible to develop it. | por |
dc.language.iso | eng | por |
dc.rights | openAccess | por |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | por |
dc.subject | Face mask | por |
dc.subject | Biosensor | por |
dc.subject | SARS-CoV-2 virus | por |
dc.subject | Sialic acid | por |
dc.title | Development of a new technology to detect respiratory infectious diseases | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
oaire.citationStartPage | 1 | por |
oaire.citationEndPage | 10 | por |
oaire.citationIssue | 52 | por |
oaire.citationVolume | 1 | por |
dc.identifier.doi | 10.56725/instemm.v1iS2.13 | por |
dc.subject.fos | Engenharia e Tecnologia::Engenharia dos Materiais | por |
sdum.journal | inSTEMM Journal | por |
oaire.version | VoR | por |
Aparece nas coleções: | DET/2C2T - Artigos em revistas internacionais com arbitragem científica |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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Instmm Journal View of Development of a sustainable biosensor to detect respiratory infectious diseases.pdf | 5,13 MB | Adobe PDF | Ver/Abrir |
Este trabalho está licenciado sob uma Licença Creative Commons