Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/46126
Título: | Solid and aqueous magnetic liposomes as nanocarriers for a new potential drug active against breast cancer |
Autor(es): | Rodrigues, Ana Rita Oliveira Silva, Pedro M. L. Almeida, B. G. Araújo, João P. Queiroz, Maria João R. P. Castanheira, Elisabete M. S. Coutinho, Paulo J. G. |
Palavras-chave: | Magnetic nanoparticles Drug delivery Magnetoliposomes New antitumor compounds |
Data: | Jan-2017 |
Editora: | Phantoms Foundation |
Resumo(s): | In this work, iron oxide nanoparticles (NPs), with diameters around 12 nm, were synthesized by coprecipitation method. Both aqueous and solid magnetic liposomes containing magnetite NPs were obtained, with sizes below 140 nm. A new antitumor compound, a diarylurea derivative of thienopyridine, active against breast cancer, was incorporated in both aqueous and solid magnetoliposomes, being located mainly in the lipid membrane. A promising application of these magnetic liposomes in oncology is anticipated, allowing a combined therapeutic approach, using both chemotherapy and magnetic hyperthermia. |
Tipo: | Resumo em ata de conferência |
URI: | https://hdl.handle.net/1822/46126 |
Versão da editora: | http://www.nanopt.org/17EN/AbstractBooK.pdf |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CDF - FAMO - Comunicações/Communications (with refereeing) CDQuim - Comunicações e Proceedings |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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NanoPT2017_abstract.pdf | Abstract | 505,42 kB | Adobe PDF | Ver/Abrir |