Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/60297
Título: | The first catalytic direct C–H arylation on C2 and C3 of thiophene ring applied to thieno-pyridines, -pyrimidines and -pyrazines |
Autor(es): | Campos, Joana F. Queiroz, Maria João R. P. Berteina-Raboin, Sabine |
Palavras-chave: | C-H activation regioselectivity thienopyridines thienopyrimidines thienopyrazines |
Data: | 30-Mar-2018 |
Editora: | Multidisciplinary Digital Publishing Institute |
Revista: | Catalysts |
Resumo(s): | A practical one-pot procedure for the preparation of diverse thieno[3,2-<i>d</i>]pyrimidines is reported here for the first time. This two-step process via C–H activation in position C-2 of thiophene led to the development of an improved methodology for the synthesis of numerous compounds. This new methodology is an efficient alternative to the conventional methods currently applied. The C–H activation of the thiophene C-3 position was also achieved and can be selective. The optimized conditions can also be applied to thienopyridines and thienopyrazines. |
Tipo: | Artigo |
Descrição: | Supplementary Materials: Supplementary materials are available online at: http://www.mdpi.com/2073-4344/ 8/4/137/s1. |
URI: | https://hdl.handle.net/1822/60297 |
DOI: | 10.3390/catal8040137 |
ISSN: | 2073-4344 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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catalysts-08-00137.pdf | 5,13 MB | Adobe PDF | Ver/Abrir |