Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/61703
Título: | Towards the reconstruction of integrated genome-scale models of metabolism and gene expression |
Autor(es): | Cruz, Fernando Lima, Diogo Faria, José P. Rocha, Miguel Dias, Oscar |
Palavras-chave: | Genome-Scale Metabolic Models Genome-scale models of metabolism and gene expression Regulation of gene expression Databases of regulatory information |
Data: | 2020 |
Editora: | Springer |
Revista: | Advances in Intelligent Systems and Computing |
Citação: | Cruz, Fernando; Lima, Diogo; Faria, José P.; Rocha, Miguel; Dias, Oscar, Towards the reconstruction of integrated genome-scale models of metabolism and gene expression. Advances in Intelligent Systems and Computing. Vol. 1005 (PACBB 2019), Springer, 173-181, 2020. |
Resumo(s): | The reconstruction of integrated genome-scale models of metabolism and gene expression has been a challenge for a while now. In fact, various methods that allow integrating reconstructions of Transcriptional Regulatory Networks, gene expression data or both into Genome-Scale Metabolic Models have been proposed. Several of these methods are surveyed in this article, which allowed identifying their strengths and weaknesses concerning the reconstruction of integrated models for multiple prokaryotic organisms. Additionally, the main resources of regulatory information were also surveyed, as the existence of novel sources of regulatory information and gene expression data may contribute for the improvement of methodologies referred herein. |
Tipo: | Artigo em ata de conferência |
URI: | https://hdl.handle.net/1822/61703 |
ISBN: | 9783030238728 |
DOI: | 10.1007/978-3-030-23873-5_21 |
ISSN: | 2194-5357 |
e-ISSN: | 2194-5365 |
Versão da editora: | https://link.springer.com/chapter/10.1007/978-3-030-23873-5_21 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_51781_1.pdf | 280,64 kB | Adobe PDF | Ver/Abrir |