Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives

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dc.contributor.authorFerreira, Paula M. T.
dc.contributor.authorMaia, Hernâni L. S.
dc.contributor.authorMonteiro, Luís S.
dc.contributor.authorSacramento, Joana
dc.contributor.authorSebastião, Joana
dc.date.accessioned2005-06-14T12:27:03Z
dc.date.available2005-06-14T12:27:03Z
dc.date.issued2000
dc.description.abstractSeveral b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine.eng
dc.distributioninternationaleng
dc.identifier.citationFerreira, P. M. T., Maia, H. L. S., Monteiro, L. S., Sacramento, J., & Sebastião, J. (2000). Synthesis of β-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives. Journal of the Chemical Society, Perkin Transactions 1. Royal Society of Chemistry (RSC). http://doi.org/10.1039/b003353geng
dc.identifier.doi10.1039/b003353gpor
dc.identifier.issn1470-4358por
dc.identifier.urihttps://hdl.handle.net/1822/2187
dc.language.isoengeng
dc.peerreviewedyeseng
dc.publisherRoyal Society of Chemistryeng
dc.rightsopenAccesseng
dc.subject.wosScience & Technologypor
dc.titleSynthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivativeseng
dc.typearticleeng
dspace.entity.typePublicationen
oaire.citationEndPage3324por
oaire.citationIssue19por
oaire.citationStartPage3317por
sdum.journalJournal of the Chemical Society, Perkin Transactions 1por

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