MicroRNA history : discovery, recent applications and next frontiers
| dc.contributor.author | Almeida, Maria Inês | |
| dc.contributor.author | Reis, R. M. | |
| dc.contributor.author | Calin, George A. | |
| dc.date.accessioned | 2012-04-17T11:14:22Z | |
| dc.date.available | 2012-04-17T11:14:22Z | |
| dc.date.issued | 2011 | |
| dc.date.submitted | 2011-11-01 | |
| dc.description | We thank the Department of Scientific Publications at The University of Texas MD Anderson Cancer Center for English language editing of the manuscript. | por |
| dc.description.abstract | Since 1993, when the first small non-coding RNA was identified, our knowledge about microRNAs has grown exponentially. In this review, we focus on the main progress in this field and discuss the most important findings under a historical perspective. In addition, we examine microRNAs as markers ofdisease diagnosis and prognosis, and as new therapeutic targets. | por |
| dc.description.sponsorship | M.I.A is supported by a PhD fellowship (SFRH/BD/47031/2008) from FCT (Fundação para a Ciência e Tecnologia) from Portugal. G.A.C. is supported as a Fellow at The University of Texas MD Anderson Research Trust, as a Fellow of The University of Texas System Regents Research Scholar, and by the CLL Global Research Foundation. Work in Dr. Calin’s laboratory was supported in part by NIH, by DoD, by 2009 Seena Magowitz – Pancreatic Cancer Action Network – AACR Pilot Grant and by the U.S./European Alliance for the Therapy of CLL. | por |
| dc.distribution | international | por |
| dc.identifier.doi | 10.1016/j.mrfmmm.2011.03.009 | por |
| dc.identifier.issn | 0027-5107 | por |
| dc.identifier.pmid | 21458467 | por |
| dc.identifier.uri | https://hdl.handle.net/1822/18666 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Elsevier | por |
| dc.relation.publisherversion | http://www.sciencedirect.com/science/article/pii/S0027510711000613 | por |
| dc.rights | openAccess | por |
| dc.subject | MicroRNAs | por |
| dc.subject | History | por |
| dc.subject | Cancer | por |
| dc.subject.wos | Science & Technology | por |
| dc.title | MicroRNA history : discovery, recent applications and next frontiers | por |
| dc.type | article | por |
| dspace.entity.type | Publication | en |
| oaire.citationEndPage | 8 | por |
| oaire.citationIssue | 1-2 | por |
| oaire.citationStartPage | 1 | por |
| oaire.citationTitle | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | por |
| oaire.citationVolume | 717 | por |
| sdum.journal | Mutation Research/fundamental and Molecular Mechanisms of Mutagenesis | por |
| sdum.publicationstatus | published | por |
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