Biomarkers of myocardial fibrosis: Revealing the natural history of fibrogenesis in fabry disease cardiomyopathy
| dc.contributor.author | Aguiar, Patrício | por |
| dc.contributor.author | Azevedo, Olga | por |
| dc.contributor.author | Pinto, Rui | por |
| dc.contributor.author | Marino, Jacira | por |
| dc.contributor.author | Cardoso, Carlos | por |
| dc.contributor.author | Sousa, Nuno | por |
| dc.contributor.author | Cunha, Damião | por |
| dc.contributor.author | Hughes, Derralynn | por |
| dc.contributor.author | Ducla Soares, José Luís | por |
| dc.date.accessioned | 2019-01-03T21:19:15Z | |
| dc.date.available | 2019-01-03T21:19:15Z | |
| dc.date.issued | 2018-03-13 | |
| dc.description.abstract | Cardiomyopathy is a major determinant of overall Fabry disease (FD) prognosis, with the worst outcomes in patients with myocardial fibrosis. Late gadolinium enhancement is currently the gold standard for evaluation of replacement myocardial fibrosis; however, this event is irreversible, thus identification of biomarkers of earlier diffuse fibrosis is paramount. | por |
| dc.description.publicationversion | info:eu-repo/semantics/publishedVersion | por |
| dc.description.sponsorship | This study has been supported by an investigator-initiated research grant from Shire Pharmaceuticals. The funder did not have a role in study design; collection, analysis, and interpretation of data; writing the report; or the decision to submit the report for publication. | por |
| dc.distribution | international | por |
| dc.identifier.doi | 10.1161/JAHA.117.007124 | por |
| dc.identifier.issn | 2047-9980 | por |
| dc.identifier.pmid | 29535138 | por |
| dc.identifier.uri | https://hdl.handle.net/1822/57763 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Wiley | por |
| dc.rights | openAccess | por |
| dc.subject | biomarkers | por |
| dc.subject | carboxyterminal propeptide of procollagen type I | por |
| dc.subject | cardiac fibrosis | por |
| dc.subject | Fabry disease cardiomyopathy | por |
| dc.subject | matrix metalloproteinases | por |
| dc.subject.wos | Science & Technology | por |
| dc.title | Biomarkers of myocardial fibrosis: Revealing the natural history of fibrogenesis in fabry disease cardiomyopathy | por |
| dc.type | article | por |
| dspace.entity.type | Publication | en |
| oaire.citationIssue | 6 | por |
| oaire.citationVolume | 7 | por |
| sdum.journal | Journal of the American Heart Association | por |
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