6-Carbohydrazonamidepurines: Convenient Precursors for 4,8-Disubstituted Pyrimido[5,4-d] pyrimidines
| dc.contributor.author | Rocha, Ashly | por |
| dc.contributor.author | Bacelar, Ana H. | por |
| dc.contributor.author | Fernandes, Joana | por |
| dc.contributor.author | Proença, M. Fernanda R. P. | por |
| dc.contributor.author | Carvalho, M. Alice | por |
| dc.date.accessioned | 2021-05-20T14:56:45Z | |
| dc.date.embargo | 10000-01-01 | |
| dc.date.issued | 2014 | |
| dc.date.submitted | 2013-09 | |
| dc.date.updated | 2021-05-19T11:06:52Z | |
| dc.description.abstract | A series of 4-arylamino-8-(alkyl or aryl)hydrazidepyrimido[5,4-d]pyrimidines was obtained efficiently from 6-carbohydrazonamidepurines by reaction with piperidine. The 6-carbo-hydrazonamidepurines were generated selectively by the reaction of 6-imidatopurine with hydrazides under acidic conditions. | por |
| dc.description.sponsorship | University of Minho and Fundação para a Ciência e Tecnologia (FCT) for financial support [project noF-COMP-01-0124-FEDER-022716 (ref. FCT PEst-/QUI/UI0686/2011) FEDER-COMPETE, FCT-Portugal, a PhD grant awarded to Ana Bacelar (SRFH/BD/24959/2005)]. The NMR spectrometer (Bruker 400 Avance III) is part of the National NMR Network supported with funds from FCT. | por |
| dc.distribution | international | por |
| dc.identifier.citation | Rocha, A., Bacelar, A. H., Fernandes, J., Proenca, M. F., & Carvalho, M. A. (2014). 6-Carbohydrazonamidepurines: Convenient Precursors for 4, 8-Disubstituted Pyrimido [5, 4-d] pyrimidines. Synlett, 25(03), 343-348 | por |
| dc.identifier.doi | 10.1055/s-0033-1340344 | por |
| dc.identifier.eissn | 1437-2096 | por |
| dc.identifier.issn | 0936-5214 | por |
| dc.identifier.uri | https://hdl.handle.net/1822/72750 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Georg Thieme Verlag | por |
| dc.relation.publisherversion | https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0033-1340344 | por |
| dc.rights | restrictedAccess | por |
| dc.subject | Rearrangement | por |
| dc.subject | Ring opening | por |
| dc.subject | Ring closure | por |
| dc.subject | Substituent effects | por |
| dc.subject | Fused-ring systems | por |
| dc.subject | Heterocycles | por |
| dc.subject.fos | Ciências Naturais::Ciências Químicas | por |
| dc.subject.wos | Science & Technology | |
| dc.title | 6-Carbohydrazonamidepurines: Convenient Precursors for 4,8-Disubstituted Pyrimido[5,4-d] pyrimidines | por |
| dc.type | article | |
| dspace.entity.type | Publication | en |
| oaire.citationEndPage | 348 | por |
| oaire.citationIssue | 3 | por |
| oaire.citationStartPage | 343 | por |
| oaire.citationVolume | 25 | por |
| sdum.export.identifier | 10708 | |
| sdum.journal | Synlett | por |
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