Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series : a structure-activity evaluation study

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dc.contributor.authorFerreira, Isabel C. F. R.
dc.contributor.authorCalhelha, Ricardo C.
dc.contributor.authorEstevinho, Letícia M.
dc.contributor.authorQueiroz, Maria João R. P.
dc.date.accessioned2005-06-16T12:00:13Z
dc.date.available2005-06-16T12:00:13Z
dc.date.issued2004
dc.description.abstractGram positive (Bacillus cereus, Bacillus subtilis), Gram negative (Pseudomonas aeruginosa, Escherichia coli) bacteria and Candida albicans as a representative of fungi were used for screening the in vitro antimicrobial activity of diarylamines in the 2,3,5-trimethyl benzo[b]thiophene series bearing different substituents, synthesised by us using the palladium-catalyzed C-N coupling methodology. The minimal inhibitory concentration (MIC) and structure-activity relationships (SARs) were evaluated.eng
dc.description.sponsorshipFundação Calouste Gulbenkian. Fundação para a Ciência e Tecnologia.por
dc.distributioninternationaleng
dc.identifier.citation“Bioorganic and medical chemistry letters”. 14 (2004) 5831-5833.eng
dc.identifier.doi10.1016/j.bmcl.2004.09.038por
dc.identifier.issn0960-894Xpor
dc.identifier.pmid15501050por
dc.identifier.urihttps://hdl.handle.net/1822/2239
dc.language.isoengeng
dc.peerreviewedyeseng
dc.publisherElseviereng
dc.rightsopenAccesseng
dc.subjectDiarylamineseng
dc.subjectAntimicrobial activityeng
dc.subjectSAReng
dc.subjectBenzothiopheneseng
dc.subject.wosScience & Technologypor
dc.titleScreening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series : a structure-activity evaluation studyeng
dc.typearticleeng
dspace.entity.typePublicationen
oaire.citationEndPage5833por
oaire.citationIssue23por
oaire.citationStartPage5831por
oaire.citationVolume14por
sdum.journalBioorganic & Medicinal Chemistry Letterspor

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