The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1

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dc.contributor.authorCasal, Margarida
dc.contributor.authorPaiva, Sandra
dc.contributor.authorAndrade, Raquel P.
dc.contributor.authorGancedo, Carlos
dc.contributor.authorLeão, Cecília
dc.date.accessioned2005-09-19T16:15:03Z
dc.date.available2005-09-19T16:15:03Z
dc.date.issued1999-01
dc.description.abstractA mutant of Saccharomyces cerevisiae deficient in the lactate-proton symport was isolated. Transformation of the mutant with a yeast genomic library allowed the isolation of the gene JEN1 that restored lactate transport. Disruption of JEN1 abolished uptake of lactate. The results indicate that, under the experimental conditions tested, no other monocarboxylate permease is able to efficiently transport lactate in S. cerevisiae.eng
dc.description.sponsorshipWe acknowledge the help of Maria J. Lafuente in the DNA sequencing and analysis and the critical reading of the manuscript by Juana M. Gancedo. This study was supported by Portuguese grant PRAXIS/2/2.1/BIO/1068/95.Work in the laboratory of C.G. was supported by grant PB97-1213-CO2-01 from the Spanish CICYT. M.C. had a FEBS short-term fellowship during the early stages of this work. S.P. received a fellowship from PRAXIS XXI-BM4229. R.P.A. received a fellowship from PRAXIS XXI-BD15737/98.por
dc.distributioninternationaleng
dc.identifier.citationCasal, M., Paiva, S., Andrade Raquel, P., Gancedo, C., & Leão, C. (1999). The Lactate-Proton Symport of Saccharomyces cerevisiae Is Encoded by JEN1. Journal of Bacteriology, 181(8), 2620-2623. doi: 10.1128/jb.181.8.2620-2623.1999eng
dc.identifier.doi10.1128/JB.181.8.2620-2623.1999
dc.identifier.eissn1098-5530
dc.identifier.issn0021-9193eng
dc.identifier.pmcPMC93691
dc.identifier.pmid10198029por
dc.identifier.pmid10198029
dc.identifier.urihttps://hdl.handle.net/1822/2971
dc.language.isoengeng
dc.peerreviewedyeseng
dc.publisherAmerican Society for Microbiology (ASM)eng
dc.relation.publisherversionhttps://journals.asm.org/doi/10.1128/JB.181.8.2620-2623.1999eng
dc.rightsopenAccesseng
dc.subject.wosScience & Technologypor
dc.titleThe lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1eng
dc.typearticlepor
dspace.entity.typePublicationen
oaire.citationEndPage2623por
oaire.citationIssue8por
oaire.citationStartPage2620por
oaire.citationVolume181por
sdum.journalJournal of Bacteriologypor
sdum.number8eng
sdum.pagination2620-2623eng
sdum.publicationstatuspublishedeng
sdum.volume181eng

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