Effect of melanomal proteins on sepia melanin assembly

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dc.commentshttp://www.3bs.uminho.pt/node/18597por
dc.contributor.authorSrisuk, Pathomthatpor
dc.contributor.authorCorrelo, V. M.por
dc.contributor.authorLeonor, I. B.por
dc.contributor.authorPalladino, Pasqualepor
dc.contributor.authorReis, R. L.por
dc.date.accessioned2015-11-23T12:32:55Z
dc.date.available2015-11-23T12:32:55Z
dc.date.issued2015-10
dc.date.submitted2015-01
dc.date.updated2015-11-09T15:54:54Z
dc.descriptionAccepted manuscriptpor
dc.description.abstractMelanins are phenol-based pigments with the potential for widespread applications including bioelectronics and tissue engineering. The concentration-dependent structural transition of sepia melanin in water is analyzed. This biopolymer at high concentration gives the well-known nanospheres, whereas sample dilution gives unforeseen nanofibres exhibiting the structural features of mature amyloid fibrils. We propose a mechanism of pigment self-assembly dependent on the interaction of residual melanosomal protein(s) with eumelanin heteropolymer. Our results contribute to understanding the peculiar physico-chemical properties of this ubiquitous pigmentpor
dc.description.sponsorshipEuropean Union's Seventh Framework Programme (FP7/2007–2013) under grant agreement No. REGPOT-CT2012–316331-POLARISpor
dc.distributioninternationalpor
dc.identifier.citationSrisuk P., Correlo V. M., Leonor I. B., Palladino P., Reis R. L. Effect of Melanomal Proteins on Sepia Melanin Assembly, Journal of Macromolecular Science, Part B: Physics, doi:10.1080/00222348.2015.1103430, 2015por
dc.identifier.doi10.1080/00222348.2015.1103430por
dc.identifier.issn0022-2348por
dc.identifier.issn1525-609Xpor
dc.identifier.urihttps://hdl.handle.net/1822/38359
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherTaylor and Francispor
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/316331/EUpor
dc.relation.publisherversionhttp://www.tandfonline.com/doi/abs/10.1080/00222348.2015.1103430por
dc.rightsopenAccesspor
dc.subjectAmyloid fibrilspor
dc.subjectAtomic force microscopypor
dc.subjectCephalopod inkpor
dc.subjectScanning electron microscopypor
dc.subjectScanning transmission electron microscopypor
dc.subjectSepia melanin self-assemblypor
dc.subject.fosCiências Médicas::Biotecnologia Médicapor
dc.subject.wosScience & Technologypor
dc.titleEffect of melanomal proteins on sepia melanin assemblypor
dc.typearticle
dspace.entity.typePublicationen
oaire.citationEndPage22por
oaire.citationIssue12por
oaire.citationStartPage1por
oaire.citationTitleJournal of Macromolecular Science Part B Physicspor
oaire.citationVolume54por
sdum.journalJournal of Macromolecular Science Part B Physicspor
sdum.publicationstatuspublishedpor

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