Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value

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dc.contributor.authorFarhat, Maha R.por
dc.contributor.authorSultana, Razvanpor
dc.contributor.authorIartchouk, Olegpor
dc.contributor.authorBozeman, Sampor
dc.contributor.authorGalagan, Jamespor
dc.contributor.authorSisk, Peterpor
dc.contributor.authorStolte, Christianpor
dc.contributor.authorNebenzahl-Guimaraes, Hannapor
dc.contributor.authorJacobson, Karenpor
dc.contributor.authorSloutsky, Alexanderpor
dc.contributor.authorKaur, Devinderpor
dc.contributor.authorPosey, Jamespor
dc.contributor.authorKreiswirth, Barry N.por
dc.contributor.authorKurepina, Nataliapor
dc.contributor.authorRigouts, Leenpor
dc.contributor.authorStreicher, Elizabeth M.por
dc.contributor.authorVictor, Tommie C.por
dc.contributor.authorWarren, Robin M.por
dc.contributor.authorvan Soolingen, Dickpor
dc.contributor.authorMurray, Meganpor
dc.date.accessioned2019-11-12T12:04:03Z
dc.date.embargo10000-01-01
dc.date.issued2016
dc.description.abstractThe development of molecular diagnostics that detect both the presence of Mycobacterium tuberculosis in clinical samples and drug resistance-conferring mutations promises to revolutionize patient care and interrupt transmission by ensuring early diagnosis. However, these tools require the identification of genetic determinants of resistance to the full range of antituberculosis drugs.por
dc.distributioninternationalpor
dc.identifier.citationFarhat, M. R., Sultana, R., Iartchouk, O., Bozeman, et. al. (2016). Genetic determinants of drug resistance in Mycobacterium tuberculosis and their diagnostic value. American journal of respiratory and critical care medicine, 194(5), 621-630por
dc.identifier.doi10.1164/rccm.201510-2091OCpor
dc.identifier.eissn1535-4970
dc.identifier.issn1073-449X
dc.identifier.pmid26910495por
dc.identifier.urihttps://hdl.handle.net/1822/62034
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherAmerican Thoracic Societypor
dc.relation.publisherversionhttps://www.atsjournals.org/doi/full/10.1164/rccm.201510-2091OCpor
dc.rightsrestrictedAccesspor
dc.subjectAntitubercular Agentspor
dc.subjectDrug Resistance, Multiple, Bacterialpor
dc.subjectGenes, Bacterialpor
dc.subjectHumanspor
dc.subjectMutationpor
dc.subjectMycobacterium tuberculosispor
dc.subjectSequence Analysis, DNApor
dc.subjectTuberculosis, Multidrug-Resistantpor
dc.subjectMolecular Diagnostic Techniquespor
dc.subjectmultidrug-resistant tuberculosispor
dc.subjectmolecular diagnosticspor
dc.subjectsensitivity and specificitypor
dc.subject.fosCiências Médicas::Medicina Básicapor
dc.subject.wosScience & Technologypor
dc.titleGenetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Valuepor
dc.typearticlepor
dspace.entity.typePublicationen
oaire.citationEndPage630por
oaire.citationIssue5por
oaire.citationStartPage621por
oaire.citationVolume194por
sdum.journalAmerican Journal of Respiratory and Critical Care Medicinepor

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