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https://hdl.handle.net/1822/2057| Título: | Synthesis and intramolecular cyclization of novel beta,beta-bis(benzo[b]thienyl)dehydroalanine derivatives |
| Autor(es): | Abreu, Ana S. Silva, Natália O. Ferreira, Paula M. T. Queiroz, Maria João R. P. |
| Palavras-chave: | Beta,beta-dibromodehydroalanine Beta,beta-bis-(benzo[b]thienyldehydroalanine Suzuki cross coupling Pyrrole derivatives β,β-bis-(benzo[b]thienyl) dehydroalanine β,β-dibromodehydroalanine |
| Data: | 2003 |
| Editora: | Elsevier 1 |
| Revista: | Tetrahedron Letters |
| Citação: | Abreu, A. S., Silva, N. O., Ferreira, P. M. T., & Queiroz, M.-J. R. P. (2003, April). Synthesis and intramolecular cyclization of novel β,β-bis-(benzo[b]thienyl)dehydroalanine derivatives. Tetrahedron Letters. Elsevier BV. http://doi.org/10.1016/s0040-4039(03)00564-1 |
| Resumo(s): | The methyl ester of tert-butyloxycarbonyl-beta,beta-dibromodehydroalanine was obtained in a one pot procedure from bis-(N-tert-butyloxycarbonyl)dehydroalanine. The former was reacted with several boronic benzo[b]thiophene acids under Suzuki cross coupling conditions, to give new beta,beta-bis-(benzo[b]thienyl)dehydroalanines in high yields. These compounds were cyclized to pyrrole derivatives by treatment with Pd(OAc)2 and Cu(OAc)2 in DMF. |
| Tipo: | Artigo |
| URI: | https://hdl.handle.net/1822/2057 |
| DOI: | 10.1016/S0040-4039(03)00564-1 |
| ISSN: | 0040-4039 |
| Arbitragem científica: | yes |
| Acesso: | Acesso aberto |
| Aparece nas coleções: | CDQuim - Artigos (Papers) |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| MJQTL03.pdf | 41,25 kB | Adobe PDF | Ver/Abrir |
