Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/20956
Título: | A simulation study comparing modeling approaches in an illness-death multi-state model |
Autor(es): | Machado, Luís Meira Faria, Susana |
Palavras-chave: | Markov process Multi-state model Proportional hazards model Simulation study Time-dependent covariate |
Data: | 2014 |
Editora: | Taylor and Francis |
Revista: | Communications in Statistics Part B: Simulation and Computation |
Resumo(s): | In many medical studies, there are covariates that change their values over time and their analysis is most often modeled using the Cox regression model. However, many of these time-dependent covariates can be expressed as an intermediate event which can be modeled using a multi-state model. Using the relationship of time-dependent (discrete) covariates and multi-state models, we compare (via simulation studies) the Cox model with time-dependent covariates with the most frequently used multi-state regression models. This paper also details the procedures for generating survival data arising from all approaches, including the Cox model with time-dependent covariates. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/20956 |
DOI: | 10.1080/03610918.2012.718841 |
ISSN: | 0361-0918 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | CMAT - Artigos em revistas com arbitragem / Papers in peer review journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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lmachadosfaria.pdf Acesso restrito! | Documento principal | 241,64 kB | Adobe PDF | Ver/Abrir |