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https://hdl.handle.net/1822/48498
Título: | Ashbya gossypii riboflavin overproducing strains are highly susceptible to light-induced oxidative DNA damage |
Autor(es): | Silva, Rui Aguiar, Tatiana Quinta Oliveira, Rui Domingues, Lucília |
Data: | 7-Dez-2017 |
Citação: | Silva, Rui; Aguiar, Tatiana Q.; Oliveira, Rui; Domingues, Lucília, Ashbya gossypii riboflavin overproducing strains are highly susceptible to light-induced oxidative DNA damage. Microbiotec'17 - Congress of Microbiology and Biotechnology 2017. No. O-25, Porto, Portugal, Dec 7-9, 61-61, 2017. |
Resumo(s): | Background The overproduction of riboflavin by Ashbya gossypii, which is one of the most distinctive traits of this filamentous hemiascomycete, is triggered by oxidative stress [1]. In turn, riboflavin is a strong photosensitizer that upon irradiation with light has been shown to generate reactive oxygen species (ROS) and induce oxidative DNA damage in mammalian cells [2-3]. Envisioning a better understanding of this A. gossypii trait, here we investigated whether riboflavin overproduction is associated with increased DNA damage. [...] |
Tipo: | Resumo em ata de conferência |
Descrição: | Microbiotec'17 - Congress of Microbiology and Biotechnology 2017 |
URI: | https://hdl.handle.net/1822/48498 |
Versão da editora: | http://www.porto.ucp.pt/pt/microbiotec17 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
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Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_47359_1.pdf | 233,31 kB | Adobe PDF | Ver/Abrir |