Label-free quantum dot conjugates for human protein IL-2 based on molecularly imprinted polymers

doi:10.1016/j.snb.2019.127343

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/62598

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Campo DC	Valor	Idioma
dc.contributor.author	Piloto, Margarida	por
dc.contributor.author	Ribeiro, David S. M.	por
dc.contributor.author	Rodrigues, S. Sofia M.	por
dc.contributor.author	Santos, João L. M.	por
dc.contributor.author	Sales, M. G. F.	por
dc.date.accessioned	2019-12-10T09:14:04Z	-
dc.date.available	2019-12-10T09:14:04Z	-
dc.date.issued	2020-02	-
dc.identifier.citation	Piloto, Margarida; David S. M. Ribeiro; S. Sofia M. Rodrigues; João L. M. Santos; Sales, M. G. F., Label-free quantum dot conjugates for human protein IL-2 based on molecularly imprinted polymers. Sensors and Actuators B-Chemical, 304(127343), 2020	por
dc.identifier.issn	0925-4005	por
dc.identifier.uri	https://hdl.handle.net/1822/62598	-
dc.description.abstract	Herein, the development of a fluorescent-based sensor by combining quantum dots (QDs) with molecularly-imprinted technology (MIP), intensively optimized to generate exceptional operating features is presented. This sensor is designed to target human interleukin-2 (IL-2) in synthetic human serum. IL-2 is a regulatory protein released as a triggered response from the immune system towards an inflammation. For this purpose, cadmium telluride (CdTe) QDs are prepared with 3-mercaptopropionic acid (MPA) and modified afterwards to produce an IL-2 imprinted polymer with methacrylic acid and N,N´-methylenebis(acrylamide), upon removal of the template under optimized conditions. During IL-2 rebinding, the fluorescence intensity of CdTe	por
dc.description.sponsorship	The authors acknowledge the ﬁnancial support of European Research Council though the Starting Grant, 3P’s Starting Grant/ERC (GA 311086) and the ﬁnancial support of Portugal 2020, FEDER and NORTE2020 through the project Strip2Sense (NORTE-01-0145-FEDER024358). AMLP also aknowledges Fundação para a Ciência e Tecnologia, I.P., for the grant reference SFRH/BPD/116067/2016.	por
dc.language.iso	eng	por
dc.publisher	Elsevier 1	por
dc.relation	info:eu-repo/grantAgreement/EC/FP7/311086/EU	por
dc.rights	openAccess	por
dc.subject	Quantum dots	por
dc.subject	molecularly imprinted polymer	por
dc.subject	conjugated-QDs	por
dc.subject	protein	por
dc.subject	interleukin-2	por
dc.subject	cancer biomarker	por
dc.title	Label-free quantum dot conjugates for human protein IL-2 based on molecularly imprinted polymers	por
dc.type	article	-
dc.peerreviewed	yes	por
dc.relation.publisherversion	https://www.journals.elsevier.com/sensors-and-actuators-b-chemical	por
dc.comments	CEB52177	por
oaire.citationVolume	304	por
dc.date.updated	2019-12-08T18:25:00Z	-
dc.identifier.doi	10.1016/j.snb.2019.127343	por
dc.description.publicationversion	info:eu-repo/semantics/publishedVersion	-
dc.subject.wos	Science & Technology	por
sdum.journal	Sensors and Actuators B: Chemical	por
Aparece nas coleções:	CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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